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Description 60-year-
Elderly male patients have a history of shortness of breath for 4 months or less
1 month fever.
In the past six months, he has gradually tightened his skin mainly on the limbs and Renault phenomenon.
The patient, a long-term smoker, has been engaged in physical labor in the past, nearly 35 years old.
Years of unprotected exposure to cement dust.
At the time of examination, skin thickening was present on the hands, face and torso (Figure 1, left panel ).
The skin check shows "skin disease of salt and pepper" (right panel in figure 1 ).
Download figureOpen in the new tabDownload powerpoint Figure 1 (left panel), which depicts the tightening of the skin on both hands.
(Right panel) changes in salt and companion skin diseases can be seen in the front chest.
CT scans of the chest showed small lymph nodes in the middle of the compartment (figure 2 left panel) and thin-
The upper lobe of the right lung has a wall cavity with surrounding nodules (panel in figure 2 ).
The X-ray of the hand shows the skin with calcium composure (figure 2 right panel ).
Anti-nuclear antibody titer increased, sputum smear positivefast bacilli.
Final Diagnosis of Erasmus syndrome (Diffuse Systemic hardening of the skin exposed to silica) and sputum smear
Tuberculosis was positive. oas_tag.
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Download figureOpen in the new tab download powerpoint Figure 2 (left panel), and chest CT scan (part of the balcony window) shows that there is a calcium stove in the lymph nodes.
(Middle panel) CT scan of the chest lung window slice shows thin
The upper right lobe has a wall cavity with surrounding nodules.
(Right panel) hand X-
Describe the rays of the calcium stove in the skin and prompt the skin calcium stove.
Erasmus syndrome describes the association of systemic hardening in general progression after exposure to silica with or without silicone lungs.
1 Our patients have a strong history of exposure to cement dust silica and have radiological signs in the form of a calcium stove in the lymph nodes of the lymph nodes.
Silicon exposure is a strong risk factor for the development of systemic hardening, and the features of silicon-related systemic hardening are not distinguished from primary epidural in clinical, serum and immunity.
In addition, even if there is no silicone lung, silicon exposure is a strong risk factor for the development of tuberculosis.
As far as we know, this is the first case report of the coexistence of Erasmus syndrome with active tuberculosis.
Learning point serasmus syndrome refers to the widespread progressive systemic hardening after exposure to silica with or without silica.
Patients exposed to silica have a high risk of tuberculosis, which persists even after stopping contact.
References chachaouch N, Mjid M, Zarrouk M, etc.
[Erasmus syndrome]tumour masses].
Revised Mal Respir 2011; 2013:924–7.
United Nations Erasmus AVIC syndrometumorales.
Openurl rustin MH, Bull HA, Ziegler V, etc. Silica-
Related systemic hardening is not different from primary systemic hardening in clinical, serum and Immunology.
Br J Dermatology Department 1990; 2013:725–34.
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