Chemical peels for acne vulgaris: a systematic review of randomised controlled trials - skin resurfacing at home

Abstract objective we evaluated the latest evidence of a randomized controlled trial (RCTs) on the effectiveness of chemical peeling in the treatment of acne with unusual conditions.
Methods Cochrane standard method was used.
In April 2017, we searched for MEDLINE, Cochrane control trial center registry and EMBASE through OvidSP.
The reviewer independently assessed the eligibility, risk of bias and the data extracted.
The results included a total of 12 randomized controlled trials (387 participants ).
There was no significant difference in effectiveness: tricloacetic acid and SA (total improvement percentage: risk ratio (RR) 0. 89; 95% CI 0. 73 to 1.
10), glycol acid (GA) and amino acid (reduced inflammatory lesions: Mean difference (MD), 0. 20; 95%u2009CI −3. 03 to 3.
43), SA for acetone (excellent or good improvement: RR 1. 11; 95%u2009CI 0. 73 to 1.
69), GA improvements to SA (good or fair: RR 1. 00; 95%u2009CI 0. 85 to 1.
18), GA and Jessner solutions (JS) (from
Report improvement: RR 1. 00; 95%u2009CI 0. 44 to 2.
26), and compare with SA (non-restore)
Inflammatory lesions: 55. 6%vs48. 5%, p=0. 878).
SA and mandel acid combined peeling is better than GA peeling (percentage improvement of total acne score: 85. 3%vs68. 5%, p